Domain adaptation is a technology enabling aided target recognition and other algorithms for environments and targets with data or labeled data that is scarce. Recent advances in unsupervised domain adaptation have demonstrated excellent performance but only when the domain shift is relatively small. We proposed targeted adversarial discriminative domain adaptation (T-ADDA), a semi-supervised domain adaptation method that extends the ADDA framework. By providing at least one labeled target image per class, used as a cue to guide the adaption, T-ADDA significantly boosts the performance of ADDA and is applicable to the challenging scenario in which the sets of targets in the source and target domains are not the same.